The cosmetics industry is undergoing a significant shift towards a more demanding beauty, driven by the increasing demand for high-performance, science-backed ingredients. Among the most promising advances are extracellular vesicles, and in particular exosomes, which have emerged as powerful mediators of intercellular communication
Once primarily investigated in the field of regenerative medicine, exosomes are now gaining considerable attention in cosmetic science for their ability to deliver bioactive molecules and modulate cellular functions in the skin.
Exosomes are nanoscale vesicles (30- 150nm) naturally secreted by virtually all kinds of cells, both in animal and plant systems. Exosomes carry a complex cargo of proteins, lipids, nucleic acids, and signaling molecules that enable them to influence diverse biological pathways. In the context of dermatology, exosomes derived from human cell cultures have demonstrated potential to stimulate central mechanisms for skin regeneration and age prevention.
While their interest in cosmetic science is rising, plant-derived exosomes remain largely underexplored due to technical challenges in their extraction, purification, characterization, and biological evaluation.
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