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Cell-to-cell communication for skin matrix repair

One of the results of ageing is that the communication process between skin cells, which is mediated by growth factors, is reduced. As a consequence, the activity of fibroblasts decreases. Unfortunately, this strongly affects the extracellular matrix (ECM), the structural network of the skin. The result of this is a reduction in the skin’s firmness, elasticity and density.

The reduced synthesis of natural growth factors affects the structural network of the skin

Without question, it is a challenge to reach dermal fibroblasts by topically-applied cosmetics. However, as these cells communicate with the keratinocytes, which are in the outer skin layers, they can be targeted by this exact communication process. This dialogue, which is crucial for a youthful appearance, is in turn mediated by growth factors that are impaired with age.

Reaching fibroblasts via intercellular communication

DermCom, from Mibelle, uses this smart strategy to successfully rejuvenate the skin matrix deep in the dermis. It stimulates the communication between epidermal and dermal skin cells by triggering keratinocytes to secrete growth factors. These growth factors enhance the synthesis of collagen and elastin in the dermis.

Clinical studies have confirmed that DermCom both improves and repairs skin texture through its growth-factor like activity. The studies have shown that it:
 
•Boosts collagen and elastin production.
•Stimulates natural growth factors of the skin.
•Renews the skin’s resilience and firmness.
 
DermCom is based on the bulbs of Crocus chrysanthus. Also known as ‘Cream Beauty’, this flower is a universal symbol of rejuvenation and youthfulness.

 Double silver award winner at in-cosmetics:

• Innovation Zone Best Ingredient Award 2012
• BSB Innovation Prize 2012

 

Upcoming Events

in-cosmetics Global

Paris Expo Porte de Versailles
16th – 18th April 2024

NYSCC Suppliers' Day 2024

Javits Center, New York
1st - 2nd May 2024

9th Anti-Ageing Skin Care Conference

Royal College of Physicians, London
25th - 26th June 2024

in-cosmetics Korea 2024

Hall C, Coex, Seoul, South Korea
24th - 26th July 2024

in-cosmetics Latin America 2024

São Paulo, Brazil
25th - 26th September 2024

IFSCC 2024

Recanto das Cataratas Thermas Resort, Iguazu Falls, Brazil
14th - 17th October 2024

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

Upcoming Events

in-cosmetics Global

Paris Expo Porte de Versailles
16th – 18th April 2024

NYSCC Suppliers' Day 2024

Javits Center, New York
1st - 2nd May 2024

9th Anti-Ageing Skin Care Conference

Royal College of Physicians, London
25th - 26th June 2024

in-cosmetics Korea 2024

Hall C, Coex, Seoul, South Korea
24th - 26th July 2024

in-cosmetics Latin America 2024

São Paulo, Brazil
25th - 26th September 2024

IFSCC 2024

Recanto das Cataratas Thermas Resort, Iguazu Falls, Brazil
14th - 17th October 2024

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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