Sederma has chosen to produce its new product, Resistem, by plant cell culture as this technology is an inexhaustible source of metabolites of interest that provides numerous benefits pertaining to sustainability, safety, quality and sourcing.
Positioned as a high tech anti-ageing ingredient, it mimics the natural hormetic phenomenon of defence. With skin being exposed daily to various stresses such as UVAB, stress, pollution, smoke, junk food, noxious agents are generated; these noxious agents lead to an accumulation of toxins in the keratinocytes which not only contributes to premature skin ageing and skin sensitivity, but which also increases redness and reduces the skin’s natural glow. Resistem is able to reproduce a hormetic response in the skin cells that develops a genuine defence system in the heart of the skin. A complex and diverse in vitro evaluation has proven Resistem’s positive effect on:
• Tissue regeneration by preservation of skin stem cells character.
• Cell detoxification by maintenance of proteasome activity.
• Cell longevity by stimulation of the sirtuin-1 synthesis.
