Targeting the five biological causes of scalp ageing

Core Biogenesis presents the clinical evaluation of a cosmetic scalp treatment containing a biomimetic FGF-2 delivered using plant-derived oleosomes

Hair thinning is one of the most common cosmetic concerns affecting both men and women worldwide. While genetic factors contribute to hair loss conditions such as androgenetic alopecia, a significant portion of hair thinning observed in the general population is associated with environmental stress, hormonal fluctuations, inflammation, and ageing of the scalp microenvironment.

Consumers often perceive hair density decline as a direct reduction in hair quantity. However, hair thinning is typically the result of several biological processes affecting both the hair follicle and the surrounding scalp tissue.

Historically, many cosmetic hair care products have focused on improving the appearance of hair fibres through conditioning polymers or film-forming ingredients. While these approaches can temporarily enhance hair volume, they do not address the biological mechanisms responsible for progressive hair thinning.

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