MARUZEN PHARMACEUTICALS CO., LTD. (MARUZEN) is a Japan-based active ingredient manufacturer with long experience, since 1938, in botanical research, extraction, and purification technologies for the cosmetic and nutraceutical industries.
MARUZEN will debut GANODERMA EXTRACT (B)-BG, a mental stress-responsive skincare active designed to support resilient skin in today’s increasingly stress-exposed environment.
Traceable Japanese Reishi Developed Through Modern Skin Research
GANODERMA EXTRACT (B)-BG is derived from the fruiting body of Reishi mushroom (Ganoderma lucidum), cultivated under fully traceable conditions in Japan. While Reishi has long been associated with wellness, this ingredient has been specifically developed for cosmetic applications by applying modern research in skin barrier biology and stress physiology.
Chronic Mental Stress as a Risk Factor for Skin Barrier Integrity
Chronic mental stress is now recognized as a significant contributor to impaired skin barrier function, increased transepidermal water loss (TEWL), and visible skin concerns. GANODERMA EXTRACT (B)-BG was developed to address this challenge at a mechanistic level, beyond conventional moisturization.
Stress-Specific Mechanism and Clinical Evidence
Supported by both highly distinctive in vitro studies and a controlled clinical study, the ingredient demonstrates regulation of intracellular cortisol balance through 11β-HSD1/2 modulation, protection of tight junction integrity, and reinforcement of barrier function under chronic stress conditions. In a double-blind, half-face clinical study conducted on highly stressed volunteers, GANODERMA EXTRACT (B)-BG significantly reduced TEWL and desquamation index, while visibly improving roughness, redness, and dark circles under the eye. Post-study questionnaires further showed higher perceived benefits on the test sample-treated side compared with placebo-treated side, highlighting both objective efficacy and consumer relevance.
From Fundamental Research to Sustainable Storytelling
From a formulation and ingredient design perspective, GANODERMA EXTRACT (B)-BG is standardized for its key active components, Ganoderic Acid A and F, ensuring consistent quality and performance. Extraction residues are recycled at the company’s own farm to cultivate new plants, contributing to sustainability claims and formulation storytelling.
Positioned for Mind-Skin and Mental Stress Care Cosmetics
GANODERMA EXTRACT (B)-BG is positioned for mental stress care and mind-skin cosmetics, aligning with the growing global focus on skin resilience and emotional well-being. The ingredient and its supporting data will be presented at Stand 3J50, where visitors can learn more about MARUZEN’s research-driven approach and Japanese-developed actives.
For those interested, please contact us via our website:
https://www.maruzenpcy.co.jp/english/form/
