Inspired by clock genes

Ashland pioneered one of the first biofunctional ingredients in the cosmetics industry to be inspired by clock genes. Now Ashland is re-introducing the novel solution Chronogen YST to provide a cosmetic solution to the deleterious effect of social jetlag on the skin.

Chronogen YST helps maintain the proper synchronisation of key day and night skin regulators, the clock genes. It is a modern age-defying approach to help strengthen the skin’s capabilities for protection and self-renewal. 

“Social jetlag is a new field of studies connected to health problems in modern societies and it is a mismatch between the body’s biological clock and sleep patterns, which can often be linked to late-night social activities such as television, online activities and personal hobbies,” said Neil Astles, global marketing and new business development manager, biofunctionals, Ashland. 

In 2017, the Nobel Prize in Physiology /Medicine was awarded for the elucidation of the molecular mechanisms controlling circadian rhythm. Each biological cell has its own clock. Clock genes are key regulators that play a significant role in 43 per cent of genes’ expression. Understanding these key cellular mechanisms inspired the development of Chronogen YST , a breakthrough in age-defying strategy in cosmetic science. 

Key applications for Chronogen YST include age defying formulations, formulations to help maintain the skin’s synchronised internal clocks, and day time formulations to help skin boost its natural defences against UV-induced damage.

 

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