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Inspired by clock genes

Ashland pioneered one of the first biofunctional ingredients in the cosmetics industry to be inspired by clock genes. Now Ashland is re-introducing the novel solution Chronogen YST to provide a cosmetic solution to the deleterious effect of social jetlag on the skin.

Chronogen YST helps maintain the proper synchronisation of key day and night skin regulators, the clock genes. It is a modern age-defying approach to help strengthen the skin’s capabilities for protection and self-renewal. 

“Social jetlag is a new field of studies connected to health problems in modern societies and it is a mismatch between the body’s biological clock and sleep patterns, which can often be linked to late-night social activities such as television, online activities and personal hobbies,” said Neil Astles, global marketing and new business development manager, biofunctionals, Ashland. 

In 2017, the Nobel Prize in Physiology /Medicine was awarded for the elucidation of the molecular mechanisms controlling circadian rhythm. Each biological cell has its own clock. Clock genes are key regulators that play a significant role in 43 per cent of genes’ expression. Understanding these key cellular mechanisms inspired the development of Chronogen YST , a breakthrough in age-defying strategy in cosmetic science. 

Key applications for Chronogen YST include age defying formulations, formulations to help maintain the skin’s synchronised internal clocks, and day time formulations to help skin boost its natural defences against UV-induced damage.

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Upcoming Events

in-cosmetics Global

Paris Expo Porte de Versailles
16th – 18th April 2024

NYSCC Suppliers' Day 2024

Javits Center, New York
1st - 2nd May 2024

9th Anti-Ageing Skin Care Conference

Royal College of Physicians, London
25th - 26th June 2024

in-cosmetics Korea 2024

Hall C, Coex, Seoul, South Korea
24th - 26th July 2024

in-cosmetics Latin America 2024

São Paulo, Brazil
25th - 26th September 2024

IFSCC 2024

Recanto das Cataratas Thermas Resort, Iguazu Falls, Brazil
14th - 17th October 2024

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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