COVER STORY: Amaretine® : Bitter-sweet synergy for sensitive skin

Sensitive skin, which typically presents as dryness, redness, itching, and an overall sensory discomfort is a sign of an impaired epidermal skin barrier and ongoing inflammatory processes. It is one of the top skin care concerns with around 60% of consumers affected worldwide, and with many experiencing a negative impact on their quality of life

With Amaretine®, Lipoid Kosmetik presents the first active ingredient to combine a bitter and a sweet component, in order to synergistically address the symptoms of sensitive skin. The bitter component andrographolide, from the plant ‘King of Bitters’, specifically binds to bitter receptors in the skin. Bitter receptors are novel and promising targets for skin care as their activation triggers the regeneration of skin barrier lipids.

The sweet component glycyrrhetinic acid, derived from licorice roots, is an excellent antiinflammatory agent. By addressing the physical symptoms such as a weak epidermal barrier, inflammation, and sensory discomfort, Amaretine® ultimately improves the quality of life of affected people.

Andrographlide activates skin barrier lipid production

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