Lehvoss Italia and Odycea examine how a marine ingredient developed from Calluna vulgaris has proven efficacy in reinforcing the epidermal barrier function, antimicrobial and antioxidant protection, hydration and cellular renewal
One vital function of skin is to form an effective barrier between the organism and the environment. This is mainly provided by the epidermis, which maintains both ‘inside-outside’ and ‘outside inside’ barriers, regulating water loss and protecting the organism from external (including mechanical, chemical and microbial) stressors, respectively. Mechanical resistance, photoprotection, antimicrobial and antioxidant defences also help to perform these essential functions
Epidermal barrier formation requires regulation of the expression of many markers, during a process called ‘terminal epidermal differentiation’, including:
The alteration of the regulation of these main components can lead to skin barrier dysfunctions, as observed during skin ageing, in sensitive skin, in altered wound healing processes and in severe inflammatory cutaneous disorders, such as psoriasis and atopic dermatitis.
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