Giancarlo Guglielmini – Sinerga, Italy
Azelaic acid is produced by the microorganism Pityrosporum ovale (and other species), which is responsible for the cutaneous disease known as “pityriasis versicolor”. This microorganism causes leucodermic spots on which melanin is not present. Its mechanism of action has been proved as a competitive inhibition of tyrosinase, the main enzyme involved in the formation of melanin.1-3
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