New studies show additional efficacy

Whitonyl, from Silab, is a natural depigmenting active ingredient, which attenuates pigment spots and gives back to the skin its uniformity and lightness, thanks to a double action on the melanogenesis and its environment.

In 2007, Silab developed Whitonyl with a focus on the major participant of melanogenesis, the melanocyte, by studying tyrosinase activity, the transport of melanosomes and SCF (Stem Cell Factor) signalling.

Thanks to innovative approaches, Silabnow presents additional efficacy data by investigating the impact of the environment on melanogenesis and the capacity of Whitonyl to regulate two pathways not studied before:

  • The epigenome of melanocytes
  • The communication via keratinocyte exosomes

Whitonyl effectively combats the signs of cutaneous photo-ageing by modulating the different mechanisms regulating melanogenesis.

The lightening and depigmenting activity of Whitonyl has been tested on the skin of Caucasian and Asian volunteers.

After 56 days of twice daily application and compared to the placebo, Whitonyl formulated at 4% lightens senescence spots by:

  • Significantly increasing parameters L* (clarity of the skin) and ITA° (degree of pigmentation);
  • Reducing parameter b* (yellow melanin pigmentation).

With Whitonyl, the skin is uniform and lightened, the complexion brightens and brown spots are attenuated.

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