Phycojuvenine DI-GPENT from CODIF TECHNOLOGIE NATURELLE is the result of 20 years of advanced scientific research in skin biology and marine biotechnology. Sourced from sustainably harvested brown algae in the cold, nutrient-rich waters of the North Atlantic, it is designed to support longevity in the skin — preserving cellular vitality and reactivating youthful functions at their core.
This new version of Phycojuvenine offers a more concentrated composition, enhancing its efficacy while maintaining the integrity of its natural marine origin.
What Does Skin Longevity Mean?
Longevity in skin is about more than just treating signs of aging. It means slowing down, stopping, and even reversing the biological processes that lead to visible and invisible deterioration. The goal is to preserve the youthful behavior, regenerative potential, and resilience of skin cells over time — ensuring high-performance skin from the inside out.
Phycojuvenine DI-GPENT Targets the 5 Entry Points of Longevity:
- Genomic Instability & Epigenetic Alterations
Phycojuvenine DI-GPENT activates sirtuins, key proteins linked to cellular longevity. This action helps limit the accumulation of DNA damage, supports genomic stability, and maintains a balanced epigenetic profile for optimal gene expression as skin ages. - Mitochondrial Dysfunction
The ingredient offers full protection of mitochondrial DNA and helps restore normal mitochondrial shape and function. This improves energy production and supports fibroblast vitality — essential for collagen synthesis and skin firmness. - Cellular Senescence
By reducing senescence markers like Sa-β-Galactosidase by 19% (in vitro), Phycojuvenine DI-GPENT helps to reactivate aged skin cells, contributing to smoother skin. - Depletion of Stem Cells
It preserves the proliferative capacity of skin cells, supporting long-term regeneration and structural integrity of the tissue.
Together, these mechanisms restore a more youthful cellular environment, enhance fibroblast activity, improve collagen production, and reinforce the extracellular matrix — all critical components of resilient, youthful-looking skin.
Proven In Vivo Performance
A 42-day clinical study conducted on women aged 50 to 70, using formulations with 1% and 2% Phycojuvenine DI-GPENT, showed visible and lasting results:
- –14.7%*** wrinkle surface area in 28 days, effect maintained at 42 days
- Remanent effect: –13.8%** wrinkle surface even one week after stopping the treatment
(Mann-Whitney test: **p<0.01; ***p<0.001)
Skin appears visibly smoother, firmer, and rejuvenated — with results that last beyond the application period.
By acting directly on the biological mechanisms of skin longevity, Phycojuvenine DI-GPENT allows the skin to reach its optimal rejuvenation effect by day 28, maintain it through day 42, and even preserve visible benefits after discontinuation — as if the skin had been reset from the effects of aging.
Conclusion
Phycojuvenine DI-GPENT from CODIF TECHNOLOGIE NATURELLE offers a unique marine-powered solution to formulate for longevity — not just treating, but actively supporting the long-term health and youthfulness of the skin. Backed by two decades of research and strong clinical data, it opens new pathways for high-performance skincare that goes beneath the surface — combining nature, science, and sustainability.
