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The anti-ageing effects of 2-aza-8-oxohypoxanthine

Vitamin C60 BioResearch Corporation has developed the world’s first cosmetic ingredient containing 2-aza-8-oxohypoxanthine (AOH), under the trade name Repista. This article describes the cellular activation effects of the AOH active ingredient on normal human epidermal keratinocytes

ABSTRACT

Vitamin C60 BioResearch Corporation has developed the world’s first cosmetic ingredient containing 2-aza-8- oxohypoxanthine (AOH), under the trade name Repista. This article describes the cellular activation effects of the AOH active ingredient on normal human epidermal keratinocytes. DNA microarray analysis using NHEKs suggested the AOH active ingredient promotes epidermal turnover, differentiation, and maturation, as well as the metabolism of old skin cells. In addition, all tests in the safety evaluation conducted on the AOH active ingredient were negative, indicating that it is a safe cosmetic ingredient. 

2-aza-8-oxohypoxanthine (AOH; Figure 1), is a plant growth factor discovered by Honorary Distinguished Professor of Shizuoka University Dr. Kawagishi.1 Until this discovery, there were only seven plant growth hormones recognized worldwide, making AOH the eighth plant growth hormone to be discovered. We expect the structure of AOH will be recognized as a major discovery and become textbook knowledge

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Upcoming Events

PCHi China 2023

The China Import and Export Fair Complex, Guangzhou
15-17 February 2023

SCSS - Conference & Laboratory Workshop

Republic Polytechnic - Woodlands Ave 9, Singapore 738964
Thur 16th & Fri 17th March 2023

in-cosmetics Global 2023 - Barcelona

Fira Barcelona Gran Via
28 - 30 March 2023

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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