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Innovative active fights Zombie cells for well-ageing

Senescence is a cellular response characterised by morphological changes, a stable growth arrest (in order to prevent tumoral proliferation) and a change in the cell’s secretome.

Indeed, senescent cells, called Zombie cells, produce a large amount of senescence-associated secretory phenotype (SASP) which is responsible for a pro-inflammatory response, for collagen degradation, for free radical production, and for the transmission of the senescent state.1 As a result, senescent cells tend to accumulate with age and 20 to 60% of the skin cells are actually senescent.2

The senescence process may be induced by several causes. Ageing is the most common phenomenon (after a certain number of division, a cell may go into senescence), but another frequent cause is stress, especially oxidative stress that induces inflammation. The combination of ageing and moderated inflammation caused by stress is called inflamm’aging, also known as “secret killer”. This progressive and insidious phenomenon has visible effects in the long term and prevents the skin from ageing well.

When a cell is exposed to stress, there are a few possible ou

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Upcoming Events

in-cosmetics Korea 2022

Hall C, Coex, Seoul, South Korea
13 - 15 July 2022

SCSS Suppliers Day - SINGAPORE

SINGAPORE MARRIOTT TANG PLAZA HOTEL
Thursday 25th & Friday 26th August 2022

32nd IFSCC Congress

Park Plaza Hotel, Westminster
19-22 September 2022

in-cosmetics Latin America 2022

Expo Center Norte, Sao Paulo
21 - 22 September

Cosmetorium 2022

Palau de Congressos de Barcelona
28 - 29 September

SEPAWA 2022

Estrel Congress Center, Berlin
26 - 28 October

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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