Anti-hair loss serum with Procapil™(*) (in vivo efficacy test)

Sederma
This ‘less is more’ serum has a light and non-greasy texture, for a maximum tolerance. It is dedicated to prevent and counteract alopecia. It has been used for Procapil™ clinical studies.
Phase 
A
ProductINCISupplier%
Water Deionised (Aqua) to 100
 Carbomer 0.25
B
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 Potassium Sorbate q.s.
C
ProductINCISupplier%
Water Deionised (Aqua) 1.60
 Sodium Hydroxide 30%  0.16
D
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 Alcohol 5.00
 Phenoxyethanol qs
 Fragrance 2 MLW0.10
E
ProductINCISupplier%
Procapil™  Sederma3.00

Preparation:
Sprinkle the carbomer in the water and allow swelling for 30 minutes. Weigh Part B. Add Part B to Part A with helice stirring (s=900 rpm). Weigh and mix Part C. Neutralise with Part C to Part A+B. Homogenize well with helice stirring (s=1000 rpm). Weigh and mix Part D. Pour Part D into Part A+B+C with helice stirring (s=1000 rpm). Add Part E and mix well.

Notes:
Appearance: Colorless limpid fluid gel; pH: 5.80± 0.5; Viscosity: 1600 cps ± 10% Sp.93, 2.5rpm, 1 min, 25°C, Brookfield DV-I Prime Stability: 3 months at 4°C, 25°C, 40°C and 1 month at 50°C; Challenge Test Validated Norm ISO 11930 Centrifuge 10min @ 3000rpm and 1 x -80ºC/+25ºC 24 hour freeze-thaw cycle and autoclave 20min @120°C

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