INdermal by Nanovex Biotechnologies presents the findings of a study that suggests improving EGF (epidermal growth factor) delivery through encapsulation may contribute to preserving extracellular matrix organization and elastic fibre integrity under chronoageing-associated conditions. Compared with non-encapsulated EGF, the encapsulated delivery system demonstrated improved biological performance both ex vivo and clinically.
Skin ageing is no longer understood solely as the appearance of wrinkles or loss of firmness, but as the progressive decline of the biological functions that allow the skin to maintain its structural integrity, adaptability and overall performance over time.
While photoageing is mainly associated with chronic ultraviolet-induced oxidative stress and inflammation, chronoageing reflects the intrinsic deterioration of the mechanisms responsible for maintaining tissue homeostasis and functional balance throughout life.1,2
For decades, cosmetic approaches to ageing mainly focused on correcting visible signs such as wrinkles, loss of firmness or uneven texture. More recently, however, concepts such as skin longevity, slow-ageing and healthy ageing have progressively shifted this perspective toward preserving skin functionality over time.
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