By identifying bioactive molecules in agricultural byproducts, argues Tel Aviv-based software developer MeNow, artificial intelligence is pushing the cosmetics industry towards circular economy principles, minimizing waste and maximizing resource efficiency
Sirtuins, particularly SIRT1, play a crucial role in cellular health, ageing, and longevity.1 This protein regulates cellular senescence, a process in which cells lose their ability to divide, contributing to skin ageing. SIRT1 also enhances DNA repair mechanisms and is essential for maintaining the skin barrier by influencing the expression of key proteins like filaggrin.2 This makes SIRT1 a highly sought-after target in anti-ageing skin care and dermatological research.
Comparatively, the retinoic acid pathway, activated by retinoids such as retinol and tretinoin, is one of the most well-known strategies for skin renewal and reversing signs of ageing.3 Retinoids work primarily by accelerating cell turnover, regulating pigmentation, and controlling sebum production, making them highly effective for improving skin texture, tone, and acne-prone conditions.4
Both SIRT1 activation and the retinoic acid pathway contribute to reducing inflammation, mitigating oxidative stress, and preserving the extracellular matrix (ECM) by supporting collagen production, reinforcing skin structure and elasticity.
Log in or register FREE to read the rest
This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text.
If you don't already have an account, please register with us completely free of charge.
