Anti-Hair Loss Serum With Procapil™(*) (In Vivo Efficacy Test)

Croda Beauty Actives (formerly Sederma)

This ‘less is more’ serum has a light and non-greasy texture, for a maximum tolerance. It is dedicated to prevent and counteract alopecia. It has been used for Procapil™ clinical studies.

Phase
Product
INCI Name
Supplier
Volume
A

Water Deionised

(Aqua)

to 100

Carbomer

0.25

B

Potassium Sorbate

q.s.

C

Water Deionised

(Aqua)

1.60

Sodium Hydroxide 30%

0.16

D

Alcohol

5.00

Phenoxyethanol

qs

Fragrance 2

MLW

0.10

E

Procapil™

Sederma

3.00

Preparation:

Sprinkle the carbomer in the water and allow swelling for 30 minutes. Weigh Part B. Add Part B to Part A with helice stirring (s=900 rpm). Weigh and mix Part C. Neutralise with Part C to Part A+B. Homogenize well with helice stirring (s=1000 rpm). Weigh and mix Part D. Pour Part D into Part A+B+C with helice stirring (s=1000 rpm). Add Part E and mix well.

Notes:

Appearance: Colorless limpid fluid gel; pH: 5.80± 0.5; Viscosity: 1600 cps ± 10% Sp.93, 2.5rpm, 1 min, 25°C, Brookfield DV-I Prime Stability: 3 months at 4°C, 25°C, 40°C and 1 month at 50°C; Challenge Test Validated Norm ISO 11930 Centrifuge 10min @ 3000rpm and 1 x -80ºC/+25ºC 24 hour freeze-thaw cycle and autoclave 20min @120°C

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