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New anti-pollution approach for skin care

DSM has developed a comprehensive approach to protect skin against the effects of environmental stressors, which the company is calling ‘Five Actives – Five Actions’. The approach has built on recent scientific advances to determine how the company’s leading actives can be applied to improve skin comfort, protection, colour, quality, and perfection.

DSM’s Personal Care business unit reveals a comprehensive new evidencebased concept that combines five leading DSM actives: Alpaflor Edelweiss, PEPHATight, PEPHA-Protect, REGUFade and Preregen PF. With their known mode of action and provenin vivoefficacy on skin appearance and sensation, these were the ideal candidates to generate anti-pollution actives. 

For the ‘Five Actives – Five Actions’ approach newin vitro studies were conducted on the pollutants urban dust (PM 2.5 & PM 10), benz(a)pyrene (BaP, a pollutant found in industrial combustion processes, car exhausts and cigarette smoke), and ozone. Focus parameters were oxidative damage, skin barrier disruption, cell viability reduction, inflammation induction, and epigenetic modulation. 

Results clearly showed that the ‘Five Actives – Five Actions’ approach helps to increase cell viability, to reduce inflammation markers IL-8 and PGE2, to modulate epigenetic marker microRNA and to reduce DNA damage. Ultimately the research distinguished five actions leading to improved skin comfort, protection, colour, quality, and perfection.

 

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Upcoming Events

in-cosmetics Global

Paris Expo Porte de Versailles
16th – 18th April 2024

NYSCC Suppliers' Day 2024

Javits Center, New York
1st - 2nd May 2024

9th Anti-Ageing Skin Care Conference

Royal College of Physicians, London
25th - 26th June 2024

in-cosmetics Korea 2024

Hall C, Coex, Seoul, South Korea
24th - 26th July 2024

in-cosmetics Latin America 2024

São Paulo, Brazil
25th - 26th September 2024

IFSCC 2024

Recanto das Cataratas Thermas Resort, Iguazu Falls, Brazil
14th - 17th October 2024

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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