Cosmetic scientists have been trying to develop a more effective ingredient to help skin absorption such as nano, liposome, and colloid. The challenge is how to measure the effectiveness of these ingredients on skin absorption.
It was decided to use a Pickering emulsion formula to study the skin’s absorption rate of active ingredients. A well known method of drug response ‘DDS (Drug Delivery System)’ using zeta potential difference was chosen to measure the skin absorption effect.
Applying Pickering emulsions that have negative potential charge to improve skin absorption within a controlled experiment mimics human skin, which has a negative potential charge too. We named this reinterpretation ADS (Active ingredient Delivery System) and it effectively increases skin absorption. Product stability and the formula’s retention period were also evaluated using zeta potential difference. The purpose of this study is to determine not only a new interpretation of zeta potential but also to establish the amount of active ingredient that results in optimum skin absorption using Pickering emulsion formula theory.
We expect this challenging area of research to open the way for a huge improvement in cosmetic formulation.
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