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Assessing skin irritation of baby products via RHE model

Personal care products specifically for babies have been around for over a century. Possibly the first supplier was Johnson & Johnson who released Baby powder in 1893 followed by Baby Cream in 1921, Baby Oil in 1938, Baby Lotion in 1942 and the benchmark for gentle shampoo, Johnson’s Baby Shampoo in 1953.

Products specifically for babies are now a well-entrenched segment of the personal care market. When developing personal care products for use on babies the difference between baby skin and adult skin needs to be considered. Babies are generally more pampered and frequently smothered in more cleansing, moisturising, massaging and soothing personal care products than most adults. This excess exposure to personal care products combined with occluding clothing and skin differences makes baby skin more susceptible to problems. 

Testing new formulations on babies is not a concept even to be considered so an alternate procedure is required. This paper will describe the differences between infant and adult skin and present a new epidermis model developed for use for in vitro toxicity testing of baby products. It will compare results of in vitro toxicology testing using this newly developed baby epidermis model and the currently available adult epidermis model.

An increase in marketing efforts for this product type has resulted in a large market segment being developed. This market has grown considerably and a typical baby personal care range is now composed of up to 15 different products as shown in Table 1. 

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Upcoming Events

in-cosmetics Global

Paris Expo Porte de Versailles
16th – 18th April 2024

NYSCC Suppliers' Day 2024

Javits Center, New York
1st - 2nd May 2024

9th Anti-Ageing Skin Care Conference

Royal College of Physicians, London
25th - 26th June 2024

in-cosmetics Korea 2024

Hall C, Coex, Seoul, South Korea
24th - 26th July 2024

in-cosmetics Latin America 2024

São Paulo, Brazil
25th - 26th September 2024

IFSCC 2024

Recanto das Cataratas Thermas Resort, Iguazu Falls, Brazil
14th - 17th October 2024

Access the latest issue of Personal Care Magazine on your mobile device together with an archive of back issues.

Download the FREE Personal Care Magazine app from your device's App store

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